Cambridge Epigenetix (@CEGX_news) have a list of almost 50 papers on their website using their technology for DNA methylation and hydroxymethylation analysis, which I thought readers of CoreGenomics might be interested in. They also have a list of Epigenetics Conferences coming up….enjoy! The papers: Chen et […]
This years #AGBT17 did not look as exciting as previous years have done, especially with all the major announcements being made at JP Morgan. In fact Illumina even went as far as to say they’d have no news at all during the conference! However there was […]
Nanostring had an interesting poster presented by Joe Beecham at last years AGBT describing their novel single-molecule hybridization-based sequencing chemistry (see AGBT and JPMorgan 2016 coverage from GenomeWeb). This utilizes the Nanostring optical barcodes in a new configuration to deliver Hyb&Seq: no amplification, no enzymes, and no […]
This article was commissioned by Genohub. If you are looking for someone to run a next-generation sequencing project for you then hopefully many of the readers of the CoreGenomics blog will have seen the googlemap of NGS instruments (watch Enseqlopedia.com/NGS-mapped for a major refresh coming soon). However the […]
In this post I describe an idea for using SNP fingerprinting for single-cell RNA-Seq to identify which sample each individual cell comes from in a multiplexed library prep. The reason for my thinking about this is that single-cell experiments are expensive. Although the cost-per-cell can […]
Andrew Adey’s group at the Department of Molecular & Medical Genetics in Oregon Health & Science University published SCI-seq in Nature Methods earlier this week (it has been on the BioRxiv since July). SCI-Seq is a method for single-cell copy number analysis that is likely […]
Introducing NovaSeq This is the second part of my “everything you wanted to know about NovaSeq blog and in it I’ll finish up by discussing some of the challenges the instrument presents for Core Labs and their users, and the costs of running NovaSeq compared to […]
Introducing NovaSeq This is the first part of a 2 part blog. Part 1 “everything you wanted to know about NovaSeq” covers the technical aspects of NovaSeq, Illumina’s latest sequencer launched on Jan 9th 2017. The instrument is very clearly the next proper step in Illumina technology, which […]
I thought I’d follow Keith’s lead and make my own suggestions for what might be revealed during Illumina’s presentation at this years JPMorgan event. All the great announcements, by Illumina and everyone else, used to be made at the AGBT meeting in February and that gave […]
Illumina’s patterned flowcells were a major change to their core technology. It was a change that was a long time coming, with patterned flowcells being discussed many years ago at AGBT. Any major change can throw up nasty surprises, and unfortunately the new ExAmp clustering […]
