24 04, 2017

Update on @illumina index-swapping: better barcode design

By | April 24th, 2017|Categories: "Experimental design controls etc", Core facilities, Methods and applications, Next-generation sequencing|Tags: , , |2 Comments

Last week I followed up on the index-swapping issue after Illumina released their white paper and also covered what Ethan Linck at The Molecular Ecologist had posted about the Sinha et al BioRxiv paper. In that post I said I’d write a follow-up post about index design over the weekend – here it is! […]

7 04, 2017

@qiagene GeneReader data published

By | April 7th, 2017|Categories: I am not a clinician, Next-generation sequencing|Tags: , |0 Comments

The Qiagen GeneReader is an NGS platform developed for the clinic and aims to deliver a sample-to-answer solution. I covered the “launch” of the instrument at the end of 2016 and summarised some of the details but there was no public data to take a […]

15 03, 2017

Cas9 CATCH-seq and lego-brick microfludics

By | March 15th, 2017|Categories: Methods and applications, Nanopore sequencing, Next-generation sequencing, Other stuff|Tags: , , |0 Comments

Two publications presenting really cool technologies recently caught my attention: “Lego for molecular biology” and “CATCH-Seq: CRISPR for target enrichment sequencing”. Both are technologies I’d like to play with, and my son can join in the Lego modelling if we build some here in Cambridge! Lego […]

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