6 03, 2023

#AGBT’23: Illumina

By | March 6th, 2023|Categories: Conferences, Core facilities, Next-generation sequencing|Tags: , |0 Comments

Continuing with my summary of what happened at #AGBT23 here’s my round up of the big announcements from Illumina. Of course whilst much of the data presented at the meeting was generated on an Illumina sequencer there was a very significant amount of non-Illumina data […]

23 02, 2023

@illumina came out fighting at JPM’22 with short and long punches – but I forgot to hit “post”!

By | February 23rd, 2023|Categories: Next-generation sequencing|Tags: , , |1 Comment

Sorry this one is over a year late – but I needed to link to it for my more recent AGBT post!James Illumina has been hugely successful in developing SBS chemistry but their lack of competition in short-read sequencing is being challenged by long-term players […]

16 02, 2023

#AGBT23: what was hot in the hottest NGS tech conference?

By | February 16th, 2023|Categories: Uncategorized|Tags: |0 Comments

I recently returned from the AGBT meeting in Sunny Florida (where it was hot) just 8 months after last years COVID delayed event. That event saw the launch of multiple new Sequencing Companies: Element Bio, Singular Genomics, and Ultima Genomics (the $100 genome company). And […]

29 09, 2022

Illumina hits back with Supernova-Seq (I wish)

By | September 29th, 2022|Categories: Next-generation sequencing|Tags: , |2 Comments

Illumina’s Innovation Roadmapjust finished and the team presented a whole lot of excitement with the new instruments: NovaSeq XPlus (available Q1 2023) and NovaSeq X (later) running XPLEAP-SBS (coming in early 2024 to NextSeq 1000 & 2000 on a new, higher output P4 flow cell) to […]

10 01, 2022

@SingularGenomic is coming to a core facility near you in 2022

By | January 10th, 2022|Categories: Core facilities, Next-generation sequencing|Tags: , , |6 Comments

The new G4 benchtop sequencer from Singular Genomics is here. Sept 17th 2021 saw the first picture of the G4 in the wild from Beth Israel Deaconess Medical Center (see below). For anyone still recovering from a 2021 New Year’s hangover, the G4 is a […]

24 11, 2017

SPLiT-Seq: single-cell RNA-Seq without the hardware

By | November 24th, 2017|Categories: Methods and applications, Next-generation sequencing, Single-cell sequencing|Tags: , , |1 Comment

I’ve been meaning to write up a post on a BioRxiv report from earlier this year: “Scaling single cell transcriptomics through split pool barcoding”1. The Seelig Lab at the University of Washington have developed a single-cell RNA sequencing method to enable labelling RNA molecules with cell-of-origin information using […]

24 04, 2017

Update on @illumina index-swapping: better barcode design

By | April 24th, 2017|Categories: "Experimental design controls etc", Core facilities, Methods and applications, Next-generation sequencing|Tags: , , |2 Comments

Last week I followed up on the index-swapping issue after Illumina released their white paper and also covered what Ethan Linck at The Molecular Ecologist had posted about the Sinha et al BioRxiv paper. In that post I said I’d write a follow-up post about index design over the weekend – here it is! […]

7 04, 2017

@qiagene GeneReader data published

By | April 7th, 2017|Categories: I am not a clinician, Next-generation sequencing|Tags: , |0 Comments

The Qiagen GeneReader is an NGS platform developed for the clinic and aims to deliver a sample-to-answer solution. I covered the “launch” of the instrument at the end of 2016 and summarised some of the details but there was no public data to take a […]

15 03, 2017

Cas9 CATCH-seq and lego-brick microfludics

By | March 15th, 2017|Categories: Methods and applications, Nanopore sequencing, Next-generation sequencing, Other stuff|Tags: , , |0 Comments

Two publications presenting really cool technologies recently caught my attention: “Lego for molecular biology” and “CATCH-Seq: CRISPR for target enrichment sequencing”. Both are technologies I’d like to play with, and my son can join in the Lego modelling if we build some here in Cambridge! Lego […]

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