A new company, Tagomics, have a very interesting pre-print: Epigenomic profiling of active regulatory elements by enrichment of unmodified CpG dinucleotides that describes their novel epigenomic profiling approach called “Active-Seq”, a bisulfite-free method designed to enrich unmethylated DNA as opposed to enriching methylated (e.g. MeDIP, GH) or everything […]
NGS would not exist without the important discussions at The Panton Arms where Illumina Next-Generation sequencing was invented…sort of. Professors Sir David Klenerman and Sir Shankar Balasubramanian are being honoured with the 2024 Novo Nordisk Prize for their pioneering work on Solexa sequencing. This led to the $1000 […]
Apparently you can do Proteomics from Qiagen AllPrep: in In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology, from Mathias Mann’s Proteomics group in Denmark, the authors presents their modifications to Qiagen’s AllPrep (DNA, RNA and protein) […]
Continuing with my summary of what happened at #AGBT23 here’s my round up of the big announcements from Illumina. Of course whilst much of the data presented at the meeting was generated on an Illumina sequencer there was a very significant amount of non-Illumina data […]
Sorry this one is over a year late – but I needed to link to it for my more recent AGBT post!James Illumina has been hugely successful in developing SBS chemistry but their lack of competition in short-read sequencing is being challenged by long-term players […]
Illumina’s Innovation Roadmapjust finished and the team presented a whole lot of excitement with the new instruments: NovaSeq XPlus (available Q1 2023) and NovaSeq X (later) running XPLEAP-SBS (coming in early 2024 to NextSeq 1000 & 2000 on a new, higher output P4 flow cell) to […]
Element Biosciences launched their AVITI sequencing platform (link to spec sheet) today and Illumina now have two new competitors in almost as many months (read my post on Singular from January). The Element pitch is to offer the highest data quality, lowest cost, and best […]
The new G4 benchtop sequencer from Singular Genomics is here. Sept 17th 2021 saw the first picture of the G4 in the wild from Beth Israel Deaconess Medical Center (see below). For anyone still recovering from a 2021 New Year’s hangover, the G4 is a […]
The news (thanks @danravicher) from the recent Illumina vs BGI_MGI that the invalidity of the ‘444 patent means BGI_MGI can enter the US market in 2022 was very interesting. Does it mean Illumina are worrying about new competition – I am not so sure. The […]
I missed the announcement last Summer on Christian Henry’s move to PacBio as their new President & CEO, taking over from Mike Hunkapiller who recently retired – these are some big boots to fill! Christian was was previously Illumina EVP and CFO, having held the CFO […]
