15 03, 2024

2024 @novonordiskfond prize to Solexa: This is why we need a pub at Addenbrookes

By | March 15th, 2024|Categories: Next-generation sequencing, Other stuff|0 Comments

NGS would not exist without the important discussions at The Panton Arms where Illumina Next-Generation sequencing was invented…sort of. Professors Sir David Klenerman and Sir Shankar Balasubramanian are being honoured with the 2024 Novo Nordisk Prize for their pioneering work on Solexa sequencing. This led to the $1000 […]

17 08, 2023

Mathias Mann Makes Multiomics Mega

By | August 17th, 2023|Categories: Methods and applications, Next-generation sequencing, Other stuff|0 Comments

Apparently you can do Proteomics from Qiagen AllPrep: in In depth profiling of the cancer proteome from the flowthrough of standard RNA-preparation kits for precision oncology, from Mathias Mann’s Proteomics group in Denmark, the authors presents their modifications to Qiagen’s AllPrep (DNA, RNA and protein) […]

6 03, 2023

#AGBT’23: Illumina

By | March 6th, 2023|Categories: Conferences, Core facilities, Next-generation sequencing|Tags: , |0 Comments

Continuing with my summary of what happened at #AGBT23 here’s my round up of the big announcements from Illumina. Of course whilst much of the data presented at the meeting was generated on an Illumina sequencer there was a very significant amount of non-Illumina data […]

23 02, 2023

@illumina came out fighting at JPM’22 with short and long punches – but I forgot to hit “post”!

By | February 23rd, 2023|Categories: Next-generation sequencing|Tags: , , |1 Comment

Sorry this one is over a year late – but I needed to link to it for my more recent AGBT post!James Illumina has been hugely successful in developing SBS chemistry but their lack of competition in short-read sequencing is being challenged by long-term players […]

29 09, 2022

Illumina hits back with Supernova-Seq (I wish)

By | September 29th, 2022|Categories: Next-generation sequencing|Tags: , |2 Comments

Illumina’s Innovation Roadmapjust finished and the team presented a whole lot of excitement with the new instruments: NovaSeq XPlus (available Q1 2023) and NovaSeq X (later) running XPLEAP-SBS (coming in early 2024 to NextSeq 1000 & 2000 on a new, higher output P4 flow cell) to […]

10 01, 2022

@SingularGenomic is coming to a core facility near you in 2022

By | January 10th, 2022|Categories: Core facilities, Next-generation sequencing|Tags: , , |6 Comments

The new G4 benchtop sequencer from Singular Genomics is here. Sept 17th 2021 saw the first picture of the G4 in the wild from Beth Israel Deaconess Medical Center (see below). For anyone still recovering from a 2021 New Year’s hangover, the G4 is a […]

21 01, 2021

@PacBio new management team knows a thing or two about sequencing ;-)

By | January 21st, 2021|Categories: Next-generation sequencing, Other stuff|0 Comments

I missed the announcement last Summer on Christian Henry’s move to PacBio as their new President & CEO, taking over from Mike Hunkapiller who recently retired – these are some big boots to fill! Christian was was previously Illumina EVP and CFO, having held the CFO […]

25 09, 2020

What is Minimal Residual Disease (MRD)?

By | September 25th, 2020|Categories: Early detection, Epigenomics, MRD, Next-generation sequencing|0 Comments

Many of my followers in the cancer space, especially the Hemes folks, will already understand what MRD is and why it’s important. But for those of you who don’t know I thought an explainer might be helpful. I took inspiration from Keiths COVID qPCR explainer and this […]

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