Two publications presenting really cool technologies recently caught my attention: “Lego for molecular biology” and “CATCH-Seq: CRISPR for target enrichment sequencing”. Both are technologies I’d like to play with, and my son can join in the Lego modelling if we build some here in Cambridge! Lego […]
Nanostring had an interesting poster presented by Joe Beecham at last years AGBT describing their novel single-molecule hybridization-based sequencing chemistry (see AGBT and JPMorgan 2016 coverage from GenomeWeb). This utilizes the Nanostring optical barcodes in a new configuration to deliver Hyb&Seq: no amplification, no enzymes, and no […]
This article was commissioned by Genohub. If you are looking for someone to run a next-generation sequencing project for you then hopefully many of the readers of the CoreGenomics blog will have seen the googlemap of NGS instruments (watch Enseqlopedia.com/NGS-mapped for a major refresh coming soon). However the […]
I thought I’d follow Keith’s lead and make my own suggestions for what might be revealed during Illumina’s presentation at this years JPMorgan event. All the great announcements, by Illumina and everyone else, used to be made at the AGBT meeting in February and that gave […]
Breast cancer researchers publish a lot of papers, and a large number of those will include some genomics, variant identification, RNA-Seq, ChIP-Seq, etc. Increasingly research is being carried out on patient derived material, but cell lines are still a vital part of much of the […]
In yesterdays Fast Company piece Christina Farr (on Twitter) gives a very nice write up of Illumina’s history and where they are going with respect to bringing DNA sequencing into the clinic. I really liked the piece and wanted to share my thoughts after reading […]
A wonderful paper in a recent edition of Science uses radiocarbon dating to show that the Greenland shark can live for up to 400 years – making it the longest lived vertebrate known. See: Eye lens radiocarbon reveals centuries of longevity in the Greenland shark (Somniosus […]
A great new resource was recently brought to my attention on Twitter and there is a paper describing it on the BioRxiv: DNAmod: the DNA modification database. Nearly all of the modified nucleotide sequencing we hear and read about is modifications to Cytosine mostly methyl cytosine […]
Today I have been working for Cancer Research UK for ten years! September 1st 2006 seems like such a short time ago but a huge amount has changed in that time in the world of Genomics. NGS has changed the way we do biology, and […]
The amount of power used in a genome analysis is not something I’d ever thought of until I heard about Optalysys, a company developing optical computing that has the potential to be 90% more energy-efficient and 20X faster than than standard (electronic) compute infrastructure. Read on if you are […]
