12 09, 2013

Patterned flowcells: what can we expect?

By | September 12th, 2013|Categories: Next-generation sequencing|1 Comment

There was a real buzz in the community when Illumina resurrected the idea of using patterned flowcells for SBS sequencing (Keith Robison covered lots of genomics news back in January, including patterned flowcells ). One of the big problems with clustering is the need to […]

3 09, 2013

Finding your way around NGS sample prep

By | September 3rd, 2013|Categories: Methods and applications, Next-generation sequencing|5 Comments

  I’m often asked which sample prep method a user should consider for their experiments. In my lab we use a lot of Illumina TruSeq kits; we’ve tried other methods, and do use Rubicon’s Thruplex, but Ilumina’s end-to-end support is useful in a medium sized […]

29 08, 2013

Targeted RNA-seq methods are here

By | August 29th, 2013|Categories: Exomes and amplicons, Methods and applications, Next-generation sequencing|2 Comments

Illumina and Life Technologies are both launching targeted RNA-seq applications which are likely to become standard tools for many labs; if the price is right. The ability to target a portion of the genome has revolutionised next-generation sequencing experiments. The analysis of exomes has exploded, […]

27 08, 2013

Back from my holidays

By | August 27th, 2013|Categories: Uncategorized|0 Comments

Two weeks away from the lab, from papers, from email and from Core Genomics – I’ve just got back from Finland’s wilderness: wood-fired sauna, lakes to swim in, fish to catch and no-one for miles; and all with fantastic 4G connection! Holidays are great and […]

23 07, 2013

Illumina’s next-gen automation solution

By | July 23rd, 2013|Categories: Other stuff|2 Comments

Illumina just bought Advanced Liquid Logic. Never heard of them until now, neither had I but I suspect we’ll see some pretty cool devices coming soon.On the ALL website they have the video below, I could not help but watch at 9sec and see PacMan […]

6 07, 2013

The GenomeWeb effect

By | July 6th, 2013|Categories: Other stuff|0 Comments

Dan Kobolt wrote a pair of articles about why he suggests you start blogging. In the first he talks about why you should, and perhaps why you would not, start blogging. I’d certainly encourage people to start, it’s fun, free and the feedback can be […]

5 07, 2013

Genome England: 100,000 genomes here we come!

By | July 5th, 2013|Categories: Uncategorized|2 Comments

We’ve waited since Christmas to find out more and on the NHS’ 65th birthday we finally get to hear more about how the NHS is going to roll out clinical sequencing for patients in England. In December last year Prime Minister David Cameron announced the […]

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