Does your lab look like this? We get most of our deliveries on dry-ice shipped from European distribution centres. All the polystyrene and dry-ice are the tip of our energy consumption iceberg. Genomics sciences have as much environmental impact as just about everything else, and […]
It’s that time of year again. The end of the financial year (for many of us) when most core facility managers get frantic calls asking if work can be billed now but done later. Lets face it this is simply a money laundering exercise but […]
Nick Loman had a nice cosy chat with Clive Brown at AGBT and tells us all about it on his blog Pathgogens: Genes and Genomes. It reads to me like a very reasonable assessment of why we have heard so little from Oxford Nanopore in […]
At regular intervals throughput the year I am asked for some help with costing next-gen sequencing experiments in grant proposals. The request usually comes towards the middle of the week leaving only a day or two before the deadline but that’s just how we work […]
There is lots of discussion about the $1000 genome, what it means, what its impact might be, etc.First off though deciding what a $1000 genome means seems to be almost impossible given everybody uses different ways to calculate costs. In a soon to be published […]
Almost…I had a very enjoyable trip to the Science Museum in London this weekend and whilst there was amazed to see an Oxford Nanopore DNA sequencing chip on display.The word on the street after ONT’s AGBT 2012 extravaganza has been more like a quiet grumble […]
Illumina’s is the most widely used next-generation sequencing technology, but like all technologies it is not perfect. You’ll have to wait for their Nanopore sequencer for perfection! One challenge we have to deal with ever more with Illumina sequencing is the balance and number of […]
De novo assembly of complex genomes is still harder than many would like.For Cancer genomes de novo assembly could be the ultimate method for discovery of all somatic events. But the analysis requires long-reads or long-insert reads and this generally eats up lots of DNA […]
The 14th AGBT meeting kicks off in one week. Unfortunately I won’t be there this year so don’t expect a daily round-up of what’s good from me! For those of you blogging and tweeting AGBT have crafted some simple graphics to indicate what you can, […]
I like encouraging people to try to come up with new ideas. One day I want to add ‘inventor’ to my CV and get a patent, I posted a while ago about an idea that came very close but was pipped to the post by […]
