I was pointed to Ethan Ford’s blog by a colleague and thought I’d recommend you take a look. Ethan is a post-doc in Ryal Lister’s lab at The University of Western Australia. The post that got me interested was one about homemade AMPure […]
The reason I wrote this post is a video I saw from Panasonic on Gizmondo, my new favourite website. However I’m going to leave the Panasonic bit to the end of this piece.Ion Torrent set AGBT on fire in 2010 with the release of the […]
I read the coverage of a CNN piece on GenomeWeb with interest; the article talks about how much costs are dropping, but alternative views were only recently aired on GenomeWeb by Neil Hall and Mick Watson, so who’s right?Back in May a commentary article by […]
Ben Raphael’s lab at Brown University have just published THetA for tumour heterogeneity analysis; it’s a great paper so download it and have a look yourselves.Solid tumours have been shown to be highly heterogeneous and that this can underlie drug resistance and eventual relapse in patients. […]
Epigenetics is one of the most exciting areas of research and promises to impact all sorts of biological systems. DNA methylation has recently been shown to come in methylcytosine (mC) and 5-hydroxymethylcytosine (5hmC) flavours. Usually analysis of mC is carried out using bisulfite conversion or […]
At the Illumina Scientific Summit in Berlin last month Prof. Philip Rosenstiel from the Christian-Albrechts-University in Kiel spoke about his work on inflammatory bowel disorder (IBD). He presented a fabulous series of experiments where mouse-models of the disease were used to show the impact of […]
This years Illumina Scientific Summit was a great meeting, lots of great talks and great people to talk to at dinner and the bar. I already posted about a collaboration Geoff Smith presented and this post is some rough notes on the “Cancer Genomics” breakout […]
Geoff Smith from Illumina presented a great piece of work his group have been collaborating on with Jill Banfield’s research group at the University of California Berkely, Department of Earth and Planetary sciences. Geoff included a discussion on their use of Moleculo.They have been using […]
The use of NGS in forensics is likely to supplant current STR profiling. One issue that has been discussed is the need to robustly determine that the correct sample has been analysed and reported on. With NGS almost all sequencing today is being done in […]
We have been running Nextera in my lab for a while now and had some great success e.g. 600x C. elegans genomes. With the release of Illumina’s rapid exome kits Nextera is proving to be a versatile and useful addition to our lab tools. Unfortunately […]
