NextSeq 500 uses a two-colour chemistry rather than the original four-colours. This makes a massive difference to the complexity of producing reagents, the instrumentation and the computation; all are effectively reduced by a factor of two. So how does it work?Update 290114: I got confirmation […]
Today I thought I’d give my first impressions on what HiSeq X Ten might mean, the dust has certainly not settled and yesterday there was lots of buzz about the new instruments from Illumina (see the bottom of this post for a round up of […]
JF did not disappoint at JPM: Jay Flatley announced both the HiSeq X Ten and NextSeq 500, two more instruments to add to HiSeq and MiSeq. HiSeq X Ten comes as ten “ultra-high throughput†sequencing instruments that together can generate 18Tb in three days, with […]
Last month I posted a logical puzzle to see if people knew how much different next-gen sequencing applications cost? The repsonses have been varied!Now Illumina have very kindly donated a MiSeq run and 250 iCredits as the prize for a festive competition. You can win […]
Given HiSeq 2500 and Ion Proton it is entirely possible for someone to sequence their genome in the Illumina or Life-Tech booth’s at AGBT, so will anyone attempt it?I am sure there would be strong interest from the AGBT community. So what’s stopping this from […]
It’s amazing what is being done with DNA sequencing. Cancer genetics and personalised medicine make headlines, consumer genomics has been in the news and Genomics England are going to sequence 100,000 NHS patients. But all that glitters is not gold! I’m not sure everyone will […]
Updated after reading Dale Yazuki’s blog pointing to this post by Lukas Hartmann, which I’ve sumarised next to Shaheen Pasha’s below.Poor old 23andMe; first the FDA and now Lisa Casey, can they survive? And what would their failure mean for personal genomics?courtesy of Genome.GovOn November […]
At our recent institute symposium I added an additional graphic to try and get people thinking about how much their sequencing costs.Can you work it out: Below are six pairs of circles representing genome, methylome, RNA-seq (GX), ChIP-seq, Exomes and amplicons, size is proportional to […]
We recently had out Institute symposium; lots of talks about the science going on in the building, mostly unpublished work and most of it very exciting. I am always amazed at how lucky I am to be working in a place that uses genomics so […]
Can some explain Myriad’s strategy, other than using bullying tactics to kill competition I don’t get it? Is there any real prospect of the law siding with their point of view? I hope not. And since the US market has some pretty wonderful advertising (surely […]
