The MRC have a nice career mapping tool: Interactive career framework which allows biomedical researchers to navigate through different options to see how they might get where they want to. I’d like to think of myself as a technology Specialist Director: “an individual with technical […]
Genomics has recently been singled out as one of the largest data headaches we face. As we move to sequencing people multiple times, start newborn genome sequencing programs and increase our use of consumer genomics the amount of data goes up and up. Our GA1 […]
Illumina have discontinued the version 1 of the NextSeq chemistry. Launched in January of last year the NextSeq was a revolutionary new sequencer, although not everyone was an immediate fan. The V2 chemistry was launched just before AGBT and the data certainly looked a lot […]
Illumina have a new offer on their Understand Your Genome (UYG) program that means you can get your genome sequenced, analysed and clinically interpreted for under £2000. Interested? Then there are a few requirements, mainly that you give informed consent and get a doctors prescription for […]
A paper just published in Nature Communications describes a molecular analysis of Pancreatic Cancer by tumour exome and ctDNA targeted sequencing. The results showed enrichment of mutations in known PaCa associated genes, and identified clinically actionable mutations in over 1/3rd of patients. Marc Sausen in […]
Researchers in the group of Yolanda Sanz in Spain deposited a preliminary MinION study describing the bioRxiv of 16S rDNA amplicon sequencing from a mock microbial community composed of genomic DNA from 20 different bacterial species (BEI Resources).Experimental workflow: 1.5kb amplicons were generated from 16S […]
The use of the pre-print servers like the original arXiv and bioRxiv appears to be growing among some of the groups I follow. You’ve only got to read Jeff Leeks post about this and their Ballgown paper (published at NatBiotech) or Nick Loman’s or Casey […]
What do 48 replicates tell you about RNA-seq DGE analysis methods: that two the most widelyâ€used of the tools DESeq and edgeR are probably the best tools for the job*. These two tools also top the rankings of RNA-seq methods as assessed by citations with […]
Back in 2010 a HiSeq 2000 cost $690,000 – you’ll be lucky to get anything today. A V4 2500 might get you $100+k, but your V4 capable V3 just $20k. Depreciation sucks!In accountancy, depreciation refers to the decrease in value of an asset over time. […]
A paper on the BioArxiv describes a new metric to measure scientific journals by based on their efficiency of information distribution (citations) within the network of journals. It provides a providing together a complex picture of the intricate relations between scientific journals; but basically Science, […]
