Updated after reading this post on GenomeWeb!Oxford University and the NHS announced the UK’s first next-generation sequencing based test for Cancer. The test uses Life Technologies Ion Torrent PGM and AmpliSeq to assay 46 gene “hotspots”, but should increase to around 150 genes in the […]
A colleague and I were discussing the woes of post-docs trying to find their next job, or a tenure-track position. My colleague was relating the story of a mutual friend who recently published an excellent first-tier publication and was still having problems finding a junior […]
I would like to move from microarray based genotyping to NGS for copy-number and loss-of-heterozygosity analysis. The copy-number bit should be relatively simple and I hope we’ll have done this by the end of the year, however the LOH analysis is more complex as it […]
Does your lab look like this? We get most of our deliveries on dry-ice shipped from European distribution centres. All the polystyrene and dry-ice are the tip of our energy consumption iceberg. Genomics sciences have as much environmental impact as just about everything else, and […]
Nick Loman had a nice cosy chat with Clive Brown at AGBT and tells us all about it on his blog Pathgogens: Genes and Genomes. It reads to me like a very reasonable assessment of why we have heard so little from Oxford Nanopore in […]
The 14th AGBT meeting kicks off in one week. Unfortunately I won’t be there this year so don’t expect a daily round-up of what’s good from me! For those of you blogging and tweeting AGBT have crafted some simple graphics to indicate what you can, […]
Two big news stories have been in the headlines in the past seven days. The first is the discovery of Richard the 3rds body, the second is the detection of Horse DNA in processed meat products. Both made me realise they are great stories to […]
Okay, so this post is completely off topic but I finally got to see “The Hobbit: an unexpected journey” and it is bad. I had been led to believe it was as good as the LOTR trilogy, friends had been to see it multiple times […]
There has been lots of news recently following the publication from Yaniv Erlich’s group at the Whitehead Institute on re-identifying individual participants in genomic studies. Anyone that has worked in forensics knows how little data is needed to unequivocally identify an individual. Erlich’s group demonstrated […]
Next-generation sequencing suffers from many of the same issues as Sanger sequencing as far as errors are concerned. The huge amounts of data generated mean we are presented with far higher numbers of variants than ever before and screening out false positives is a very […]
