A recent circulating tumour DNA (ctDNA) paper describes a comparison of ctDNA to CTC’s with respect to TP53 mutations in 40 triple negative breast cancer patients. See: Circulating tumour DNA and circulating tumour cells in metastatic triple negative breast cancer patients in the International Journal […]
The 250bp paired-end HiSeq rapid run kits are almost here! Expect to get 150M reads per lane or more on the current rapid flowcells. What will you do with 150M 500bp OPES?No word on pricing yet, and I could not find any PE250 data on […]
I was chatting with a colleague at work who’d asked me if I know anywhere they could get their genome or exome sequenced. My genome has been sat in the freezer for over five years wanting to go onto a flow cell, but I’ve never […]
I’ve been inspired to create three Twitterbots for NGS papers on @RNA-seq, @ChIP-seq and @Exome-seq by Casey Bergman at the University of Manchester. I’d not come across Caseys twitter account (I don’t actually use Twitter that much) or his lab website and blog; but I […]
Registration is open! The registration process for AGBT has been overhauled in the last few years; yes there’s still a lot of people who don’t get in, but it seems to be pretty fair. Countdown WidgetsI hope to see you there. I’m going to be blogging […]
Why does blogger’s spell check try to correct ‘blog’, and why does it suggest ‘bog’ or ‘blag’. Are they telling me I’m writing s**t or trying to get something for free?Please fix this one blogger.com.
This morning someone made the 500,000th page view on the CoreGenomics blog. It amazes me that so many people are reading this and the last couple of years writing have been really good fun. I’ve met many readers and some fellow bloggers, and received lots […]
I’m speaking at the BaseSpace Apps developers conference in Bangalore tomorrow. It’s my first App and my first time in India, so I’m pretty excited about the whole thing.Earlier this year Matt Eldridge (Head of Bioinformatics) and I published a little paper on our sequencing […]
Inivata, is a new company spun out of Nitzan Rosenfelds research group at the CRUK Cambridge Institute (where I work). His group developed and published the TAm-seq method for circulating tumour DNA amplicon sequencing. The spin-out aims to develop blood tests measuring circulating tumour DNA […]
I’ve heard lots of presentations about novel sequencing technologies, many have never arrived, some have come and gone, all have been pretty neat ideas; but so far not one has arrived that outperforms the Illumina systems many readers of this blog are using.Base4’s pyrophosphorolysis sequencing […]
