9 10, 2014

Twitterbots for NGS

By | October 9th, 2014|Categories: Uncategorized|0 Comments

I’ve been inspired to create three Twitterbots for NGS papers on @RNA-seq, @ChIP-seq and @Exome-seq by Casey Bergman at the University of Manchester. I’d not come across Caseys twitter account (I don’t actually use Twitter that much) or his lab website and blog; but I […]

7 10, 2014

Count-down to AGBT 2015

By | October 7th, 2014|Categories: Uncategorized|0 Comments

Registration is open! The registration process for AGBT has been overhauled in the last few years; yes there’s still a lot of people who don’t get in, but it seems to be pretty fair. Countdown WidgetsI hope to see you there. I’m going to be blogging […]

29 09, 2014

Thanks for reading

By | September 29th, 2014|Categories: Uncategorized|0 Comments

This morning someone made the 500,000th page view on the CoreGenomics blog. It amazes me that so many people are reading this and the last couple of years writing have been really good fun. I’ve met many readers and some fellow bloggers, and received lots […]

28 09, 2014

Making BaseSpace Apps in Bangalore

By | September 28th, 2014|Categories: Uncategorized|3 Comments

I’m speaking at the BaseSpace Apps developers conference in Bangalore tomorrow. It’s my first App and my first time in India, so I’m pretty excited about the whole thing.Earlier this year Matt Eldridge (Head of Bioinformatics) and I published a little paper on our sequencing […]

4 09, 2014

The newest sequencer on the block: Base4 goes public

By | September 4th, 2014|Categories: Uncategorized|3 Comments

I’ve heard lots of presentations about novel sequencing technologies, many have never arrived, some have come and gone, all have been pretty neat ideas; but so far not one has arrived that outperforms the Illumina systems many readers of this blog are using.Base4’s pyrophosphorolysis sequencing […]

4 09, 2014

Low-diversity sequencing: RRBS made easy

By | September 4th, 2014|Categories: Uncategorized|2 Comments

Illumina recently released a new version of HCS v2.2.38 for the HiSeq. The update improves cluster definition significantly and enables low-diversity sequencing. It’s a great update and one that’s making a big impact on a couple of projects here. Better RRBS: the current RRBS protocols […]

4 09, 2014

Low-diversity sequencing: RRBS made easy

By | September 4th, 2014|Categories: Uncategorized|0 Comments

Illumina recently released a new version of HCS v2.2.38 for the HiSeq. The update improves cluster definition significantly and enables low-diversity sequencing. It’s a great update and one that’s making a big impact on a couple of projects here. Better RRBS: the current RRBS protocols […]

28 08, 2014

SEQC kills microarrays: not quite

By | August 28th, 2014|Categories: Uncategorized|1 Comment

I’ve been working with microarrays since 2000 and ever since RNA-seq came on the scene the writing has been on the wall. RNA-seq has so many advantages over arrays that we’ve been recommending them as the best way to generate differential gene expression data for […]

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