18 11, 2013

96 ChIPs? That’ll fit on one of Illumina’s new patterned flowcells

By | November 18th, 2013|Categories: Uncategorized|2 Comments

ENCODE was a mammoth endeavor, and one that is helping to better shape our understanding of biology, but the project required a large multi-national collaboration to generate the 1000’s of ChIP-seq and RNA-seq libraries. Last week Duncan Odom’s research group at the Cambridge Institute published an […]

15 11, 2013

How to access BaseSpace forums

By | November 15th, 2013|Categories: Uncategorized|1 Comment

If you are using Illumina’s BaseSpace then you probably run into some of the same frustrations as myself and other users, however Illumina do provide a feedback mechanism and a forum to suggest ideas for development. Finding this can be a bit difficult so in […]

12 11, 2013

PubMed commons: how will we use it?

By | November 12th, 2013|Categories: Uncategorized|4 Comments

PubMed commons is hoping to create somewhere for researchers to “share their opinions about scientific publications”, it is going to be for “open and constructive criticism and discussion of scientific issues” and will “depend on the scientific quality of the interchange”. Your comments are made […]

8 11, 2013

Personal Genome Project UK and Dr Evil’s frame-up

By | November 8th, 2013|Categories: Uncategorized|1 Comment

–>George Church started something great back in 2005, now Stephan Beck at the UCL Cancer Centre has kicked off the UK’s own Personal Genome Project. The idea has always been a simple one, get data from willing participants, make genome sequencing free and make the […]

22 10, 2013

Bioinformatics at the top

By | October 22nd, 2013|Categories: Uncategorized|0 Comments

A few years ago one of our junior group leaders made an interesting appointment; he recruited a bioinformatician into a research assistant role. Every lab has someone, or several people, who keep the lab running. They are the people making sure cells get cultured, supporting […]

21 10, 2013

Genomics England is go

By | October 21st, 2013|Categories: Uncategorized|1 Comment

Genomics England is steaming ahead to sequence 100,000 genomes from NHS patients. Today Genomics England and Illumina announced their intention to start the 1st 10,000 genomes as part of a seqeucning contract run by Illumina.   Set up by the Department of Health and announced […]

4 10, 2013

It’s not Open Acess’s fault!

By | October 4th, 2013|Categories: Uncategorized|0 Comments

Update: …see the bottom of the post for more coverage on this “sting”GenomeWeb has coverage of a story all of us should take a look at. A fake manuscript produced by a journalist from Science was accepted by 157 open-access publishers, a damning indictment of […]

23 09, 2013

Circulating RNA analysis

By | September 23rd, 2013|Categories: Uncategorized|0 Comments

Analysis of circulating DNA has had a major impact in the last couple of years with 100s of publications in the last few years. I’ve previously posted about work at the Institute on circulating tumour DNA analysis of amplicons and exomes, but what about RNA?RNAs […]

27 08, 2013

Back from my holidays

By | August 27th, 2013|Categories: Uncategorized|0 Comments

Two weeks away from the lab, from papers, from email and from Core Genomics – I’ve just got back from Finland’s wilderness: wood-fired sauna, lakes to swim in, fish to catch and no-one for miles; and all with fantastic 4G connection! Holidays are great and […]

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