8 04, 2015

Rise of the Nanopore

By | April 8th, 2015|Categories: Uncategorized|1 Comment

Nature Methods recently carried a News & Views article from Nick Loman and Mick Watson: “Successful test launch for nanopore sequencingâ€, in which they discuss the early reports of MinION usage; including a paper in the same issue of Nature Methods (Jain et al). They […]

20 03, 2015

Oxford Nanopore MinION for ctDNA sequencing

By | March 20th, 2015|Categories: Uncategorized|0 Comments

A great poster at AGBT was presented by Boreal Genomics and available on the Nanopore wiki for MAPpers. In A nanopore liquid biopsy Patrick Davies describes their combination of the Boreal On-Target with ONT MinION sequencing to detect mutant allele fractions in ctDNA of sub […]

14 03, 2015

Fancy working in my lab?

By | March 14th, 2015|Categories: Uncategorized|0 Comments

I’ve currently got three positions open in my lab and thought I’d use this blog as another way to get the message out to prospective candidates. Two people recently moved onto new jobs; one in Inivata (the first spin-out from CRUK-CI) and one at AbCam, […]

13 03, 2015

A better way to sequence exomes?

By | March 13th, 2015|Categories: Uncategorized|2 Comments

I caught up with a new company on the target capture scene, Directed Genomics, at AGBT. Their approach is based on a simple idea: if you want to sequence exomes, why not capture only exons? Most exome-seq methods (Illumina, Agilent, Nimblegen) use oligo-baits to pull-down […]

10 03, 2015

In silico prescription of cancer drugs is likely to benefit patients – and can only get better

By | March 10th, 2015|Categories: Uncategorized|7 Comments

A fantastic paper just out in Cancer Cell: In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities from Nuria Lopez-Bigas’s BioMedical Genomics lab in Barcelona.They have developed an in silico prescription strategy by identifying the driver events in TCGA […]

28 02, 2015

AGBT 2015 review…sort of

By | February 28th, 2015|Categories: Uncategorized|0 Comments

Another fun year at AGBT in sunny Marco Island. There has been some good blog coverage this year, but not from me; I’ve been Tweeting instead @CIgenomics on #AGBT15, see what happened on Twitter.The UCSC Twitter trackBlog coverage: GenomeWeb were there for those who could […]

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