How big would ABI377 plates need to be to deliver NovaSeq X Plus output?
I asked ChatGPT this question one evening and working through the session was fun. Maybe it needs more fact-checking...I know some of my readers are fastidious enough to call me out if I'm wrong but here goes. When I started in Genomics it was still called [...]
cfDNA fragmentomics reviewed
This is a fantastic and comprehensive review on Cell-free DNA fragmentomics in cancer. Out in Cancer Cell by Denis Lo et al. In this review focused on cell-free DNA (cfDNA) fragmentomics in the context of cancer diagnostics the authors explore how analyzing cfDNA fragmentation patterns can provide new [...]
Unlocking the Potential of Urine-Based Liquid Biopsies
I'm really pleased to say I'm an author on a new article in Nature Cancer discussing the potential of using urine-based liquid biopsies for cancer detection, particularly through the analysis of circulating-cell-free-tumor DNA in urine (utDNA, cufDNA or ucpDNA). While urine offers advantages because it is [...]
The Future of At-Home Oncology Testing: Tiny Drops, Big Insights?
The journey for an oncology patient often involves a relentless cycle of clinic visits, treatments, and crucially to the work I am involved with, blood draws for diagnosis, monitoring and MRD. This routine, while essential, presents significant burdens – from travel and time off work to [...]
The word according to Fred
And Fred said, let there be sequence: and there were sequencers.
Roche emerges from the Lazarus pit
Is Roche going to "knock it out of the park" or "jump the shark"? Everyone I know is excited, even if many of them are sceptical, about the Feb 20th webinar and what we will learn about SBX. Alex Dickinson appears to be driving most of the buzz, having [...]