Okay, so this post is completely off topic but I finally got to see “The Hobbit: an unexpected journey” and it is bad. I had been led to believe it was as good as the LOTR trilogy, friends had been to see it multiple times […]
There has been lots of news recently following the publication from Yaniv Erlich’s group at the Whitehead Institute on re-identifying individual participants in genomic studies. Anyone that has worked in forensics knows how little data is needed to unequivocally identify an individual. Erlich’s group demonstrated […]
Next-generation sequencing suffers from many of the same issues as Sanger sequencing as far as errors are concerned. The huge amounts of data generated mean we are presented with far higher numbers of variants than ever before and screening out false positives is a very […]
Social networking and commenting or reviewing on websites are part of the run-of-the-mill for most of today’s web users. Who would book a hotel without checking TripAdvisor for instance? Even finding a plumber is made easier with sites like Mybuilder!There are many other “social-networking” sites […]
There is an ongoing debate about consumer genetics. Companies such as 23andMe can provide what appear to be rich datasets on the surface but comparisons of results between companies can lead to different conclusions, the raw data can also differ although where the same arrays […]
At the 2012 Illumina European scientific summit just outside Barcelona in June Sean Humphray presented work on HiSeq 2500 sequencing of clinical genomes. The results were pretty stunning with very nice data, generated and analysed in under a week, it really looked like we were […]
Update: the cufflinks referred to on GenomeWeb have now sold and made £60 for charity. If you would like me to put another pair on eBay leave a comment below and I’ll add a link. I posted last year a picture of some Ion Torrent […]
Today the Primer Minister of the UK, David Cameron, visited the Cancer Research UK Cambridge Research Institute and my lab!L-R: Fatimah, Hannah, Claire, Sarah, James Brenton, David Cameron (holding a MiSeq flowcell) and me!We had only a little warning he was coming and had to […]
A recent Lancet paper (Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcusaureus: a descriptive study) describes work in the Rosie’s special care bay unit at Addenbrookes hospital in Cambridge (just across the road from where I work).The group studied a putative outbreak of […]
I am often asked for a good NGS reference, or references that explain the technology used in next generation sequencing experiments. I have gathered together a list of my favourites over the past few years and thought readers of this blog might like to see […]
